At Prema we use a corneal transplants technique known as Endothelial Keratoplasty (EK).

Treatment at a glance

Treatment Time

Up to 60 mins

Anaesthetic

Local anaesthetic

Downtime

7 - 14 days

Price

From £9000 per eye

Key Benefit

Improve vision

Corneal Transplants
Corneal Transplants

Clear vision often relies on the clarity of the cornea. If the endothelial cell layer, which is very delicate, has become damaged or is starting to malfunction the cornea can start to cloud over – a condition known as a cataract. When this condition has begun to develop it will continue to progress, as this cellular layer can not be regenerated and repaired naturally. A cloudy cornea, or cataract, will impair vision and the only way to correct it would be to replace this layer of cells with a donor layer.

During the corneal transplants procedure the affected layer of corneal cells is removed, and a layer of donated human cells are put in their place. To do this Prema uses the DSAEK (Descemet’s Stripping Automated Endothelial Keratoplasty) procedure. This approach involves the implantation of a thin layer of connective tissue carrying the required cells, which is 60-120 microns thick. This method helps to restore lost vision when the innermost layer of corneal cells (endothelium) are not functioning in the way they should.

What are the benefits of Corneal Transplants?

  • Improved vision
  • Treat corneal failure / decompensation
  • Cataract surgery can be combined
Corneal Transplants
Prema Aesthetics

How Is It Performed?

1.Local anaesthetic is administered (general anaesthetic can be used).
2.Eyes are cleaned with Povidone iodine clean and a sterile drape is applied
3.The eyelid support is inserted.
4.The affected corneal endothelium is removed and the donor cornea endothelial transplant is inserted.
5.Graft is secured in place with air or an SF6 bubble which holds the graft against the inside of the cornea.
6.Topical anti-inflammatory and antibiotic drops are applied, and the patient is advised to lie flat on back as much as possible (45 minutes in every hour) for the first 2-3 days post-surgery.

How Is It Performed?

1.Local anaesthetic is administered (general anaesthetic can be used).
2.Eyes are cleaned with Povidone iodine clean and a sterile drape is applied
3.The eyelid support is inserted.
4.The affected corneal endothelium is removed and the donor cornea endothelial transplant is inserted.
5.Graft is secured in place with air or an SF6 bubble which holds the graft against the inside of the cornea.
6.Topical anti-inflammatory and antibiotic drops are applied, and the patient is advised to lie flat on back as much as possible (45 minutes in every hour) for the first 2-3 days post-surgery.

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Corneal transplants can help to correct a number of eye conditions, including: cataract, Fuch’s dystrophy, bullous keratopathy, blurry vision, cloudy vision, glare and iridocorneal endothelial (ICE) syndrome. With the DSAEK procedure surgeons will only replace the affected layer of the cornea without disturbing any healthy, functioning cells.

Corneal Transplants
Corneal Transplants Corneal Transplants
Frequently Asked Questions

Frequently asked questions

DSAEK differs from DMEK (Descemet’s Membrane Endothelial Keratoplasty) as it includes the stromal (connective) tissues within the transplant. This means that it can be more effective than the ‘like-for-like’ approach with DMEK.

The recovery period for both DSAEK and DMEK is around 1-4 weeks, depending on the patient’s individual response. Patients can expect their vision to be a little poor for the first few days, improving once the bubble has moved above the pupil. If glasses are required, we would wait for around 6 weeks to assess the prescription needed.

Patients may feel their vision is worse after the procedure than it was before. This is to be expected as the front chamber of the eye will be filled with gas /air, and will improve once the bubble is reabsorbed. In the first few days, it would be normal for the operated eye to see light and blurred shapes, and reading may not be possible. As air floats on water, the bubble will move upwards before disappearing completely after 5 / 7 days. The operated eye may also feel gritty and / or itchy, and Prema will provide medication as part of the aftercare plan

Prema takes great care of their patients, and severe complications are uncommon. However, our surgeons ensure patients are informed of all potential risks which may include: infection, elevated intraocular pressure, allergies and graft dehiscence or dislocation.

Both DSAEK and DMEK can be undertaken in around 30 minutes. The procedure is performed under local anaesthetic and can be combined with cataract surgery if this is required.

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